Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2006-04-17
2008-11-11
Tsang, Cecilia J (Department: 1654)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C514S003100, C514S008100, C514S012200, C514S056000, C604S500000
Reexamination Certificate
active
07449200
ABSTRACT:
The invention discloses the biodegradable nanoparticle for use in nanoparticle projectile bombardment as a carrier for administering proteins or peptides to an animal subject. The nanoparticles are composed of positively charged shell substrate, negatively charged core substrate with encapsulated bioactive agents of proteins or peptides.
REFERENCES:
patent: 6194389 (2001-02-01), Johnston et al.
patent: 6475995 (2002-11-01), Roy et al.
Lin YH et al., “Preparation of nanoparticles composed of chitosan/poly-r-glutamic acid and evaluation of their permeability through Caco-2 cells” Biomacromolecules 2005;6:1104.
Chen Mei-Chin
Lee Po-Wei
Sung Hsing-Wen
Tu Hosheng
Cordero Garcia Marcela M
GP Medical, Inc.
National Tsing Hua Univeristy
Tsang Cecilia J
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