Nanoparticles for paracellular drug delivery

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Reexamination Certificate

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Details

C514S055000

Reexamination Certificate

active

11029082

ABSTRACT:
The invention discloses the nanoparticles composed of chitosan/poly-γ-glutamic acid characterized with a positive surface charge and their enhanced permeability through Caco-2 cells for paracellular drug delivery.

REFERENCES:
patent: 5254342 (1993-10-01), Shen et al.
patent: 6086918 (2000-07-01), Stern et al.
patent: 6730661 (2004-05-01), Kiliaan et al.
van der Lubben et al., Eur. J. Pharm. Sci., 14, 2001, 201-207.

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