Nanoparticles for monoclonal antibody delivery

Drug – bio-affecting and body treating compositions – Immunoglobulin – antiserum – antibody – or antibody fragment,...

Reexamination Certificate

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C977S733000, C977S915000, C514S002600

Reexamination Certificate

active

07541028

ABSTRACT:
The invention discloses the nanoparticles composed of chitosan, poly-glutamic acid, and at least one bioactive agent of monoclonal antibody. The nanoparticles are characterized with a positive surface charge and their enhanced permeability for paracellular drug delivery.

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Product Information “Humira” by Abbott Laboratories, North Chicage, Illinois, Oct. 2005.

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