Nanoparticles comprising at least one polymer and at least...

Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form

Reexamination Certificate

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Details

C424S499000, C424S502000

Reexamination Certificate

active

06881421

ABSTRACT:
Nanoparticles containing at least one active ingredient including at least one polymer, preferably a poly(alkylcyanoacrylate), in which the alkyl group, linear or branched, contains from 1 to 12 carbon atoms, and of at least one compound able to complex said active ingredient. The invention also concerns the method for preparing these nanoparticles.

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patent: WO 9204916 (1992-04-01), None
patent: WO 9325195 (1993-12-01), None
Dominique Duchêne et al, “Cyclodextrins in targeting Application to nanoparticles,” 1999, Advanced Drug Delivery Reviews, pp. 29-40, XP-002104026.
Airton Monza da Silveira et al, “Combined Poly(isobutylcyanoacrylate) and Cyclodextrins Nanoparticles for Enhancing the Encapsulation of Lipophilac Drugs,” 1998, Pharmaceutical Research, vol. 15, No. 7, pp. 1051-1055, XP-002085312.
Elias Fattal et al, “Biodegradable polyalkylcyanoacrylate nanoparticles for the delivery of oligonucleotides,” 1998, Journal of Controlled Release 53, pp. 137-143.
Niteen Bapat et al, “Uptake Capacity and Adsorption Isotherms of Doxorubicin on Polymeric Nanoparticles: Effect of Methods of Preparation,” 1992, Drug Dev. Ind. Pharm., 18, pp. 65-77, XP-002085319.
Patrick Couvreur, “Polyalkylcyanoacrylates as Colloidal Drug Carriers,” 1988, Crc Crit. Rev. Ther. Drug Carrier Syst., vol. 5, Issue 1, XP-002085327.

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