Nanoparticles and microparticles of non-linear hydrophilic-hydro

Details Nanoparticles and microparticles of non-linear hydrophilic-hydro Nanoparticles and microparticles of non-linear hydrophilic-hydro

1994-06-24

1996-11-26

Azpuru, Carlos

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Particulate form

424489, 424497, 424498, 424501, 424502, 424451, 424462, 424 7808, 5147723, 514784, 514963, 42840221, 42840224, 428403, A61K 950, A61K 948, A61K 3174, A61K 4730

Patent

active

055783252

ABSTRACT:
Injectable particles are provided that are not rapidly cleared from the blood stream by the macrophages of the reticuloendothelial system, and that can be modified as necessary to achieve variable release rates or to target specific cells or organs as desired. The injectable particles can include magnetic particles or radiopaque materials for diagnostic imaging, biologically active molecules to be delivered to a site, or compounds for targeting the particles. Biodistribution experiments indicate that the injectable particles have a prolonged half-life in the blood compared to particles not containing poly(alkylene glycol) moieties on the surface.

REFERENCES:
patent: 4801739 (1989-01-01), Franz et al.
patent: 4904479 (1990-02-01), Illum
patent: 5410016 (1995-04-01), Hubbell et al.

Affiliated with

Also associated with

Rating

Nanoparticles and microparticles of non-linear hydrophilic-hydro does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Nanoparticles and microparticles of non-linear hydrophilic-hydro, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nanoparticles and microparticles of non-linear hydrophilic-hydro will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1971228