Chemistry: analytical and immunological testing – Involving an insoluble carrier for immobilizing immunochemicals – Carrier is inorganic
Reexamination Certificate
2008-04-29
2008-04-29
Chin, Christopher L. (Department: 1641)
Chemistry: analytical and immunological testing
Involving an insoluble carrier for immobilizing immunochemicals
Carrier is inorganic
C435S006120, C436S525000, C436S527000, C436S173000
Reexamination Certificate
active
07364919
ABSTRACT:
Materials and methods for studying and modulating the interaction of carbohydrate-containing moieties with other species are described, in particular, small particles, e.g. clusters of metal or semiconductor atoms, which can be employed as a substrate for immobilizing a plurality of ligands comprising carbohydrate groups. These “nanoparticles” can then be used to study carbohydrate mediated interactions, e.g. with other carbohydrates or proteins, and as therapeutics and diagnostic reagents.
REFERENCES:
patent: 4313734 (1982-02-01), Leuvering
patent: 5248772 (1993-09-01), Siiman et al.
patent: 5766572 (1998-06-01), Hasegawa et al.
patent: 6132750 (2000-10-01), Perrier et al.
patent: 0 465 081 (1992-01-01), None
patent: 2 777 193 (1998-04-01), None
patent: WO83/00173 (1983-05-01), None
patent: WO89/03675 (1989-05-01), None
patent: WO95/31220 (1995-11-01), None
patent: WO 99/61911 (1999-12-01), None
WPI Accession No. 1996-010697/01 (Abstract).
Ada, “Vaccines and Vaccination”, N. Engl. J. Med., vol. 345, No. 14, pp. 1042-1053 (2001).
Boal, et al., “Self-assembly of nanoparticles into structures spherical and network aggregates”; Nature. vol. 404, pp. 746-748 (2000).
Brown and London, “Structure of Detergent-Resistant Membrane Domains: Does Phase Separation Occure in Biological Membranes?”, Biochemical and Biophysical Research Communications, 240, pp. 1-7 (1997).
Brust, et al., “Synthesis and Reactions of Functionalised Gold Nanoparticles”; J. Chem Soc., Chem. Commun., pp. 1655-1656 (1995).
Coteron, et al., “Glycophanes, Cyclodextrin-Cyclophane Hybrid Receptors for Apolar Binding in Aqeous Solutions. A Stereoselective Carbohydrate-Carbohydrate interaction in Water”; J. Am. Chem. Soc., vol. 115, No. 22, pp. 10066-10076 (1993).
Eggens, et al., “Specific Interacton between Le×and Le×Determinants”, The Journal of Biological Chemistry, vol. 264, No. 16, pp. 9476-9484 (1989).
Fitzmaurice, et al., “Heterosupramolecular Chemistry: Programmed Pseudorotaxane Assembly at the Surface of a Nanocrystal”, Angew. Chem. Int. Ed. vol. 38, No. 8, pp. 1147-1150 (1999).
Frey, et al., “Role of the Glycocalyx in Regulating Access of Microparticles to Apical Plasma Membranes of Intestinal Epithelial Cells: Implications for Microbial Attachment and Oral Vaccine Targeting”, J. Exp. Med., vol. 184, pp. 1045-1059 (1996).
Hakomori, “Carbohydrate-carbohydrate interaction as an initial step in cell recognition”, Pure & Appl. Chem., vol. 63, No. 4, pp. 473-482 (1991).
Hakomori, et al., “New insights in glycosphingolipid function: ‘glycosignaling domain,’ a cell surface assembly of glycosphingolipids with signal transducer molecules, involved in cell adhesion coupled with signaling”, Glycobiology, vol. 8, No. 10, pp. xi-xix (1998).
Horan, et al., “Nonstatistical binding of a protein to clustered carbohydrates”, PNAS, vol. 96, No. 21, pp. 11782-11786 (1999).
Jiménez-Barbero, et al., “Molecular Recognition of Carbohydrates Using a Synthetic Receptor. A Model System To Understand the Stereoselectivity of a Carbohydrate-Carbohydrate Interaction in Water”, J. Am. Chem. Soc., vol. 117, No. 45, pp. 11198-11204 (1995).
Kiessling and Pohl, “Strength in numbers: non-natural polyvalent carbohydrate derivatives”, Chemistry & Biology, vol. 3, No. 2, pp. 71-77 (1996).
Nitov, et al., “Shiga-like toxins are neutralized by tailored multivalent carbohydrate ligands”, Nature, vol. 403, pp. 669-672 (2000).
Klarreich, “Biologists join the dots”, Nature, vol. 413, pp. 450-452 (2001).
Liang, et al., “Polyvalent binding to carbohydrates immobilized on an insoluble resin”, Proc. Natl. Acad. Sci. USA, vol. 94, pp. 10554-10559 (1997).
Liu, et al., “Cyclodextrin-Modified Gold Nanospheres. Host-Guest Interactions at Work to Control Colloidal Properties”, J. Am. Chem. Soc., vol. 121, pp. 4304-4305 (1999).
Mammen, et al., “Polyvalent Interactions in Biological Systems: Implications for Design and Use of Multivalent Ligands and Inhibitors”, Angew. Chem. Int. Ed., vol. 37, pp. 2754-2794 (1998).
Misevic, “Molecular Self-Recognition and Adhesion via Proteoglycan to Proteoglycan Interactions as a Pathyway to Multicellularity: Atomic Force Microscopy and Color Coded Bead Measurements in Sponges”, Microscopy Research and Technique, vol. 44, pp. 304-309 (1999).
Morales, et al., “Carbohydrate-Carbohydrate Interactions in Water with Glycophanes as Model Systems”, J. Org. Chem. vol. 63, pp. 9212-9222 (1998).
Nilsson and Mandenlus, “A Carbohydrate Biosensor Surface for the Detection of Uropathogenic Bacteria”, Bio/Technology, vol. 12, pp. 1376-1378 (1994).
Revell, et al., “Self-Assembled Carbohydrate Monolayers: Formation and Surface Selective Molecular Recognition”, Langmuir, vol. 14, pp. 4517-4524 (1998).
Schmidt and Jung, “Oligosaccharide Synthesis with Trichloroacetimidates”, pp. 283-312.
Simons and Ikonen, “Functional rafts in cell membrances”, Nature, vol. 387, pp. 569-572 (1997).
Storhoff and Mirkin, “Programmed Materials Synthesis with DNA”, Chem. Rev., vol. 99, No. 7, pp. 1849-1862 (1999).
Strömberg, et al., “Saccharide orientation at the cell surface affects glycolipid receptor function”, Proc. Natl. Acad. Sci. USA, vol. 88, pp. 9340-9344 (1991).
Taton, et al., “Scanometric DNA Array Detection with Nanoparticle Probes”, Science, vol. 289, pp. 1757-1760 (2000).
Templeton, et al., “Monolayer-Protected Cluster Molecules”, Acc. Chem. Res., vol. 33, No. 1, pp. 27-36 (2000).
Templeton, et al., “Water-Soluble, Isolable Gold Clusters Protected by Tiopronin and Coenzyme A Monolayers”, Langmuir, vol. 15, pp. 66-76 (1999).
Weigel, et al., “Adhesion of Hepatocytes to Immobilized Sugars”, Journal of Biological Chemistry, vol. 254, No. 21, pp. 10830-10838 (1979).
Weis and Drickamer, “Structural basis of lectin-carbohydrate recognition”, Annu. Rev. Biochem., vol. 65, pp. 441-473 (1996).
Zutshi, et al., Inhibiting the assembly of protein-protein interfaces, Current Opinion in Chemical Biology, vol. 2, pp. 62-66 (1998).
Moore et al., “Tumoral Distribution of Long-Circulating Dextran-Coated Iron Oxide Nanoparticles in a Rodent Model”, Radiology 2000 United States, vol. 214, No. 2, 2000, pp. 568-574.
European Search Report (Re: EP 05 02 6069).
Tromas, C., et al. “Adhesion Forces Between Lewis Determinant Antigens AsMeasured By Atomic Force Microscopy”, Angew. Chem. Int. Ed. 2001, 40, No. 16, pp. 3052-3055, May 5, 2001.
de la Fuente, et al. “Gold Glyconanoparticles As Water-Soluble Polyvalent Models To Study Carbohydrate Interactions”, Angew. Chem. Int. Ed. 2001, 40, No. 12, pp. 2258-2261, Jan. 19, 2001.
Bell G.I., et al. “Cell Adhesion: Competition Between Nonspecific Repulsion and Specific Binding.”Biophys. J45: 1051-1064 (1984).
Houseman B.T., et al. “The Role of Ligand Density in the Enzymatic Glycosylation of Carbohydrates Presented on Self-Assembely Mononlayers of Alkanethiolates on Gold.”Angew. Chem. Int. Ed. 38(6): 782-785 (1999).
Yarema K.J., et al., “Chemical Approaches to Glycobiology and Emerging Carbohydrate-Based Therapeutic Agents.”Curr. Opin. Chem. Biol. 2(1): 49-61 (1998).
Martin-Lomas Manuel
Penades Soledad
Rojo Javier
Chin Christopher L.
Edwards Angell Palmer & & Dodge LLP
Lauro, Esq. Peter C.
Midatech Limited
LandOfFree
Nanoparticles does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nanoparticles, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nanoparticles will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2769617