Drug – bio-affecting and body treating compositions – Preparations characterized by special physical form – Particulate form
Reexamination Certificate
2007-03-13
2007-03-13
Woodward, Michael P. (Department: 1615)
Drug, bio-affecting and body treating compositions
Preparations characterized by special physical form
Particulate form
C424S009100, C424S489000, C424S400000, C514S772000, C514S782000, C977S773000, C977S776000, C977S831000
Reexamination Certificate
active
10427242
ABSTRACT:
The present invention relates to a colloidal dispersion of amine-terminated silica particles having a narrowly controlled size range in an aqueous phase for use in diagnostic imaging, drug delivery and gene therapy, as well as methods for preparing surface-modified silica particles suitable for use in an aqueous colloidal carrier medium, for preparing a diagnostic or therapeutic agent for targeted delivery to specific anatomical structures of a patient, and for performing a diagnostic or therapeutic procedure by administration to a patient of at least one diagnostic or therapeutic agent coupled with a colloidal dispersion.
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Chen I-Wei
Choi Hoon
Rivise Caesar
Silverman Eric E.
The Trustees of the University of Pennsylvania
Woodward Michael P.
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