Chemistry: electrical and wave energy – Apparatus – Electrolytic
Patent
1998-03-19
2000-09-26
Warden, Jill
Chemistry: electrical and wave energy
Apparatus
Electrolytic
204412, G01N 2726
Patent
active
061238198
ABSTRACT:
An array of electrodes at the atomic or nano scale (nanoelectrodes) is built on a chip. The spatial distribution, height, width and electrochemical composition of the nanoelectrodes is varied, such that protein-specific electronic receptors are built directly on the chip with the nanoelectrodes without the use of any specific binding agents or molecules. Because of their size, a very large number of different receptors can be built as arrays on a single chip. The chip can be used to detect, characterize and quantify single molecules in solution such as individual proteins, complex protein mixtures, DNA or other molecules.
REFERENCES:
patent: H201 (1987-01-01), Yager
patent: 4452682 (1984-06-01), Takata et al.
patent: 4568444 (1986-02-01), Nakamura et al.
patent: 4777019 (1988-10-01), Dandekar
patent: 4908112 (1990-03-01), Pace
patent: 4981572 (1991-01-01), Eastmunt et al.
patent: 4983510 (1991-01-01), Lardinois et al.
patent: 5019238 (1991-05-01), Cormier et al.
patent: 5156810 (1992-10-01), Ribi
patent: 5192507 (1993-03-01), Taylor et al.
patent: 5281539 (1994-01-01), Schramm
patent: 5310469 (1994-05-01), Cunningham et al.
patent: 5328847 (1994-07-01), Case et al.
patent: 5332479 (1994-07-01), Uenoyama et al.
patent: 5384028 (1995-01-01), Ito
patent: 5395587 (1995-03-01), Brigham-Burke et al.
patent: 5409583 (1995-04-01), Yoshioka et al.
patent: 5494831 (1996-02-01), Kindler
patent: 5532128 (1996-07-01), Eggers et al.
patent: 5567301 (1996-10-01), Stetter et al.
patent: 5582697 (1996-12-01), Ikeda et al.
patent: 5607567 (1997-03-01), Yun et al.
patent: 5624537 (1997-04-01), Turner et al.
patent: 5730940 (1998-03-01), Nakagawa
patent: 5795782 (1997-08-01), Church et al.
patent: 5910286 (1999-06-01), Lipsker
CAPLUS abstract of Clowes et al. ("Improved methods for structural studies of proteins using nuclear magnetic resonance spectrotroscopy", Curr. opin. Biotechnol. (1995, 6(1), 81-8).
P. 45 of "Principles of Biological Chemistry" by David Page, Willard Grant Press, 1976.
JAPIO abstract of Hajme et al. (JP 02276966), Nov. 1990.
CAPLUS abstract of Costa-Kramer et al. ("Metallic nanowires: conductance statistics, stability, IV curves, and magnetism", NATO ASI Set., Ser. E (1997), 340 (nanowires), 171-190).
D.M. Kolb, R. Ullmann, T. Will, "Nanofabrication of Small Copper Clusters on Gold (111) Electrodes by a Scanning Tunneling Microscope". Science Magazine, vol. 275, Feb. 21, 1997, pp. 1097-1099.
Leo Kouwenhoven, "Single-Molecule Transistors". Science Magazine, vol. 275, Mar. 28, 1997, pp. 1897-1898.
Science, Jun. 11, 1999, vol. 284, p. 1754, article entitled "From the Bioweapons Trenches, New Tools for Battling Microbes".
Noguerda Alex
Protiveris, Inc.
Warden Jill
LandOfFree
Nanoelectrode arrays does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Nanoelectrode arrays, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Nanoelectrode arrays will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-2096737