Nano-calcium phosphates/collagen based bone substitute...

Details Nano-calcium phosphates/collagen based bone substitute... Nano-calcium phosphates/collagen based bone substitute...

2005-05-03

2005-05-03

Naff, David M. (Department: 1651)

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Implant or insert

C424S093700, C435S176000, C435S177000, C435S395000

Reexamination Certificate

active

06887488

ABSTRACT:
The present invention relates to a nano-calcium phosphates/collagen composite that mimics the natural bone, both in composition and microstructure, as well as porous bone substitute and tissue engineering scaffolds made by a complex of said composite and poly(lactic acid)(PLA) or poly(lactic acid-co-glycolic acid)(PLGA). The invention also relates to the use of said scaffold in treating bone defect and bone fracture.

REFERENCES:
patent: 5626861 (1997-05-01), Laurencin et al.
patent: 6013591 (2000-01-01), Ying et al.
patent: 6331312 (2001-12-01), Lee et al.
patent: WO 0003747 (2000-01-01), None

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