NANBV diagnostics and vaccines

Details NANBV diagnostics and vaccines NANBV diagnostics and vaccines

2005-03-01

2005-03-01

Zeman, Mary K. (Department: 1631)

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

C435S007100, C435S948000, C435S960000, C436S501000, C436S538000, C436S063000, C436S086000, C436S811000, C436S820000

Reexamination Certificate

active

06861212

ABSTRACT:
A family of cDNA sequences derived from hepatitis C virus (HCV) are provided. These sequences encode antigens which react immunologically with antibodies present in individuals with non-A non-B hepatitis (NANBH), but which are absent from individuals infected with hepatitis A virus, or hepatitis B virus, and also are absent in control individuals. The HCV cDNA sequences lack substantial homology to the sequences of hepatitis delta virus (HDV) and HBV. A comparison of the sequences of amino acids encoded in the HCV cDNA with the sequences of Flaviviruses indicates that HCV may be related to the Flaviviruses.The HCV cDNA sequences and the polypeptides encoded therein are useful as reagents for the detection and therapy of HCV. The reagents provided in the invention are also useful for the isolation of NANBH agent(s), for the propagation of these agents in tissue culture, and for the screening of antiviral agents for HCV.

REFERENCES:
patent: 4271145 (1981-06-01), Wands
patent: 4356164 (1982-10-01), Tabor
patent: 4395395 (1983-07-01), Tabor
patent: 4464474 (1984-08-01), Coursaget
patent: 4491632 (1985-01-01), Wands
patent: 4659678 (1987-04-01), Forrest et al.
patent: 4673634 (1987-06-01), Seto
patent: 4683195 (1987-07-01), Mullis et al.
patent: 4683202 (1987-07-01), Mullis et al.
patent: 4702909 (1987-10-01), Villarejos et al.
patent: 4870026 (1989-09-01), Wands
patent: 4871659 (1989-10-01), Pillot
patent: 4891313 (1990-01-01), Berger et al.
patent: 5077193 (1991-12-01), Mishiro et al.
patent: 5098704 (1992-03-01), Valenzuela
patent: 5106726 (1992-04-01), Wang
patent: 5191064 (1993-03-01), Arima et al.
patent: 5218099 (1993-06-01), Reyes et al.
patent: 5372928 (1994-12-01), Miyamura et al.
patent: 5436126 (1995-07-01), Wang
patent: 5856437 (1999-01-01), Miyamura et al.
patent: 5871903 (1999-02-01), Miyamura et al.
patent: 5959092 (1999-09-01), Miyamura et al.
patent: 3697989 (1989-11-01), None
patent: 8910967 (1989-11-01), None
patent: 5812390 (1990-12-01), None
patent: 0061974 (1982-01-01), None
patent: 0190972 (1986-08-01), None
patent: 0194207 (1986-10-01), None
patent: 0263761 (1988-04-01), None
patent: 0279460 (1988-07-01), None
patent: 0277437 (1988-08-01), None
patent: 88400790 (1988-11-01), None
patent: 0318216 (1989-05-01), None
patent: 0388232 (1990-09-01), None
patent: 0442394 (1991-08-01), None
patent: 0293274 (1991-09-01), None
patent: 0468527 (1992-01-01), None
patent: 2239245 (1991-06-01), None
patent: 2239245 (1991-06-01), None
patent: 2212511 (1992-01-01), None
patent: 1836291983 (1983-10-01), None
patent: 02-500880 (1990-03-01), None
patent: 5-81600 (1993-11-01), None
patent: 77108060 (1992-07-01), None
patent: WO 8203330 (1982-02-01), None
patent: WO 8202774 (1982-03-01), None
patent: WO 8200205 (1982-06-01), None
patent: WO 8705930 (1987-01-01), None
patent: WO 8803410 (1988-05-01), None
patent: WO 8904669 (1989-06-01), None
patent: WO 8905855 (1989-06-01), None
patent: WO 8910967 (1989-11-01), None
patent: WO 9011089 (1990-10-01), None
patent: WO 9014436 (1990-11-01), None
patent: WO 9115516 (1991-01-01), None
patent: WO 9300365 (1993-01-01), None
patent: WO 9708310 (1997-06-01), None
Valenzuela et al. 1982 Nature vol. 298 p 347, Jul. 22, 1982.*
Valenzuela et al. 1985 Biotechnology vol. 3 p 323, Apr. 1, 1985.*
Petrovskis et al., “Use of λgt11 To Isolate Genes for Two Pseudorabies Virus Glycoproteins with Homology to Herpes Simplex Virus and Varicella-Zoster Virus Glycoproteins,”J. of Immunology60(1):185-193 (185-193 (1986).
Purcell, “Blood-Borne Non-A, Non-B Hepatitis,”Update2:2 (1988).
Rice et al., “Molecular Cloning of Flavivirus Genomes for Comparitive Analysis and Expression,”Modern Trends in Virology, pp. 83-97 (1988).
Geysen et al., “Strategies for epitope analysis using peptide synthesis,”J. of Immununological Methods102:259-274 (1987).
Maynard et al., “Transmission of Non-A, Non-B Hepatitis by Blood Products and Plasma Derivatives,”Non-A, Non-B HepatitisChapter 5, pp. 71-95 (1981).
Tohmatsu et al., “AN6520 Ag: An Antigen Purified from Liver With Non-A, Non-B Hepatitis,”J. of Medical Virology15:357-371 (1985).
Daniel W. Bradley v Chiron Corporation, Civil Action No. 94-4342, Order Granting Defendant's Motion to Strike Allegations from and to Dismiss Second Amended Complaint on Jul. 15, 1996.
Daniel W. Bradley v Chiron Corporation, Civil Action No. 94-4342, Judgment on Jul. 25, 1996.
Deposition of Gregory R. Reyes, vol. 1, Sep. 11, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.); Deposition pp. 1-183 & Index pp. 1-17.
Deposition of Gregory R. Reyes, vol. II, Oct. 4, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd. et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 201-325, Index pp. 1-10.
Deposition of Stephen M. Feinstone, M.D., Jun. 26, 2000, In Chiron Corp v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 1-170, Index pp. 1-18.
Deposition of Gordon P. Erspamer, vol. I, Jul. 18, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 1-174, Index pp. 1-21.
Deposition of Gordon P. Erspamer, vol. II, Sep. 28, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 175-308, Index pp. 1-17.
Deposition of Dr. Alfred Prince, Sep. 21, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 1-80, Index pp. 1-7.
Deposition of Shirley S.W. Wong-Chen, Sep. 26, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 1-134, Index pp. 1-15.
Deposition of Donald S. Chisum, Aug. 15, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 1-312, Index pp. 1-30.
Deposition (Videotaped) of Martha Ann Truett, vol. I, Jun. 6, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 1-221, Index pp. 1-22.
Deposition (Videotaped) of Martha Ann Truett, vol. II, Jun. 7, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 222-430, Index pp. 1-22.
Deposition (Videotaped) of Martha Ann Truett, vol. III, Aug. 9, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 431-589, Index pp. 1-19.
Deposition of Michael S. Urdea, Ph.D, vol. I, Feb. 16, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 1-200, Index pp. 1-22.
Deposition of Michael S. Urdea, Ph.D, vol. II, Feb. 17, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 202-392, Index pp. 1-22.
Deposition of Michael S. Urdea, Ph.D., vol. III, Feb. 18, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 393-521, Index pp. 1-16.
Deposition (Videotaped) of Amy J. Weiner, Ph.D., vol. I, Aug. 17, 2000, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 1-291, Index pp. 1-30.
Deposition of George Kuo, Ph.D., vol. I, Nov. 8, 1999, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 1-244, Index pp. 1-23.
Deposition of George Kuo, Ph.D., vol. II, Nov. 9, 1999, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 245-477, Index pp. 1-23.
Deposition of George Kuo, Ph.D., vol. III, Nov. 11, 1999, In Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 478-648, Index pp. 1-19.
Deposition of Qui Lim Choo, Ph.D., vol. I, Dec. 15, 1999, In Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 1-165, Index pp. 1-15.
Deposition of Qui Lim Choo, Ph.D., vol. II, Dec. 16, 1999, in Chiron Corp. v. Hoffman-La Roche, Ltd., et al., No. C 98-0315 CW (N.D. Cal.), Deposition pp. 166-359, Index pp. 1-18.
Deposition of Qui Lim Choo, Ph.D., vol. III, Dec. 17, 1999, in Chiron

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