Nail lacquer for the treatment of onychomycosis

Details Nail lacquer for the treatment of onychomycosis Nail lacquer for the treatment of onychomycosis

1993-04-08

1994-09-13

Page, Thurman K.

Drug, bio-affecting and body treating compositions

Manicure or pedicure compositions

A61K 7043

Patent

active

053466926

ABSTRACT:
The invention relates to a nail lacquer for treating onychomycosis, comprised of a film-forming agent, an antimycotically active substance, and urea, wherewith the antimycotically active substance and the urea are liberated from the lacquer when the lacquer is applied. A preferred formulation comprises cellulose derivative(s) as film former(s), clotrimazole as the antimycotic (present in the amount of 5-30 wt. % based on the weight of the non-volatile components), urea (present in the amount of 15-60 wt. % based on the weight of the non-volatile components), and dibutyl phthalate as a plasticizer, in a solvent mixture comprised of acetone and ethanol.

REFERENCES:
patent: 4180058 (1979-12-01), Brem
patent: 4721724 (1988-01-01), Stettendorf et al.
patent: 4957730 (1990-09-01), Bohn et al.
patent: 5120530 (1992-06-01), Ferro et al.
Chemical Abstracts, vol. 96, No. 20, 1982, AM-168622k.

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