Nabilone granulation

Drug – bio-affecting and body treating compositions – Lymphokine

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424283, A61K 3179

Patent

active

041950780

ABSTRACT:
A solution of nabilone and PVP in anhydrous ethanol is used to granulate ethanol-insoluble pharmaceutically-acceptable excipients such as starch.

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Thakker et al. J. Pharm. Pharmacol. 29(12): 783-784 (1977) "Solid Dispersion Approach for Overcoming Bioavailability Problems due to Polymorphism of Nabilone, a Cannabinoid Derivative".
Rubin et al. Clin. Pharmacol. Ther. 1977: 22(1): 89-91 "Physiologic Disposition of Nabilone, a Cannabinol Derivative, in Man".
Newton, J. M. et al. J. Pharm. Pharmacol 1977: 29(5): 294-297 The Influence of Additions on the Presentation of a Drug in Hard Gelatin Capsules.
Doelker et al. J. Pharm. Pharmacol. 29(4):193-198 (1977) The Effect of Some Binding Agents on Mechanical Properties of Granules.
Lemberger et al. Cli. Pharmacol. 18(6): 720-726 (1975) Clinical Pharmacology of Nabilone, a Cannabinol Derivative.

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