N-trityl and N-phenylfluorenyl carboxyanhydrides of amino acids

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

560 41, 562445, 562443, C07D26344

Patent

active

060938315

ABSTRACT:
Amino acids are derivatized for use in peptide synthesis by conversion to N-carboxyanhydrides that are N-proected by either a trityl or a phenylfluorenyl group.

REFERENCES:
K. Barlos et al., J. Org. chem. (1982) 47: 1324-1326..
H. Block and M.E. Cox, "Proceedings of the 5.sup.th European Peptide Symposium, Oxford, 1962," Pergamon Press, Oxford (1963).
B.D. Christie and H. Rapoport, J. Org. Chem. (1985) 1239-1246.
R.G. Denkewalter et al., J. Am. Chem. Soc. (1969) 91(2): 502-503.
W.D. Fuller et al., J. Am. Chem. Soc. (1990) 112: 7414-7416.
P.Gmeiner et al., J. Org. Chem. (1990) 55: 3068-3074.
J.J. Leban and K.L. Colson, J. Org. Chem. (1996) 61:228-231.
M. Mutter and Rene Hersperger, Synthesis (Mar. 1989) 198-200.
C. Palomo et al., J. Chem. Soc., Chem. Commun. (1995) 2327-2328.
C. Palomo et al., Chem. Commun., (1996) 1269-1270.
C. Palomo et al., J. Org. Chem. (1996) 61: 4400-4404.
T.T. Romoff and M. Goodman, J. Peptide Res. (1997) 49: 281-292.
H.R. Kricheldorf, Angew, Chem. (1973) 85(2): 86-87.
L. Zervas and D.M. Theodoropoulos, J. Am. Chem. Soc. (Apr. 5, 1956) 78: 1359-1363.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

N-trityl and N-phenylfluorenyl carboxyanhydrides of amino acids does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-trityl and N-phenylfluorenyl carboxyanhydrides of amino acids, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-trityl and N-phenylfluorenyl carboxyanhydrides of amino acids will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1337567

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.