N-Trifluoroacetyladriamycin-14-O-hemiglutarate and -hemiadipate

Details N-Trifluoroacetyladriamycin-14-O-hemiglutarate and -hemiadipate N-Trifluoroacetyladriamycin-14-O-hemiglutarate and -hemiadipate

1980-06-09

1981-11-10

Brown, Johnnie R.

Drug, bio-affecting and body treating compositions

Conjugate or complex of monoclonal or polyclonal antibody,...

Conjugated via claimed linking group, bond, chelating agent,...

536 17A, C07H 1524, A61K 3171

Patent

active

042998220

ABSTRACT:
N-Trifluoroacetyladriamycin-14-O-hemiglutarate and -hemiadipate having antitumor activity and low toxicity are soluble in water at a physiological pH ranging from 7.2 to 7.5.

REFERENCES:
patent: 4035566 (1977-07-01), Israel et al.
patent: 4166848 (1979-09-01), Bernardi et al.

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