N-tetrazolyl thiazolecarboxyamide derivatives and their use

Details N-tetrazolyl thiazolecarboxyamide derivatives and their use N-tetrazolyl thiazolecarboxyamide derivatives and their use

1987-09-17

1989-11-07

Gerstl, Robert

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514314, 514326, 514342, 514365, 544405, 546167, 546209, 546276, 548200, C07D41712, C07D41714

Patent

active

048792950

ABSTRACT:
Compounds of the formula: ##STR1## wherein A is a C.sub.1-6 alkyl group, an aryl group which is unsubstituted or substituted with at least one substituent selected from hydroxy, alkoxy, aryl-(C.sub.1-6)alkoxy, C.sub.1-6 alkylcarbonyloxy, halo-(C.sub.1-6)alkyl, halogen, nitro and amino,

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patent: 4526979 (1985-07-01), Peet et al.
patent: 4558059 (1985-12-01), Kawasaki et al.
patent: 4567193 (1986-01-01), Peet et al.
Hargrave, et al., Journal of Med. Chem., vol. 26, p. 1158 (1983).
Peet, et al., Journal of Med. Chem., vol. 29, p. 538 (1986).
European Search Report application No. EP 87 30 8481.
Journal of Med. Chem., "Synthesis and Quantitative Structure-Activity Relationships of Antiallergic 2-Hydroxy-N-1H-tertrazol-5-ylbenzamides and N-(2-Hydroxyphenyl)-1H-tetrazole-5-carboxyamides", Ford, et al., vol. 29, p. 538, (1986).
Journal of Med. Chem., "Antiallergic Agents. 2.sup.1. N-(1H-Tetrazol-5-yl)-6-phenyl-2-pyridinecarboxamides", Honma, et al., vol. 26, p. 1499 (1983).
Chemical Abstracts, vol. 79 (15) p. 441, No. 92204b.

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