N-terminus modified analogs of LHRH

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

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530313, 530327, 530328, C07K 1459

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active

055020356

ABSTRACT:
Decapaptide and undecapaptides substituted on the N-terminal nitrogen atom by acyl groups which include furo-2-yl, isonicotinyl, nicotinyl, 2-, 3-, and 4-quinolinecarbonyl, shikimyl, dihydroshikimyl, and tetrahydrofur-2-oyl are potent antagonists of LHRH and are useful for suppressing the levels of sex hormones in mammals.

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