N-Terminal substituted oligopeptide converting enzyme inhibitors

Details N-Terminal substituted oligopeptide converting enzyme inhibitors N-Terminal substituted oligopeptide converting enzyme inhibitors

1983-02-18

1984-11-20

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

424200, 424258, 424274, 2601125K, A61K 3700, A01N 5700, A01N 4342, A01N 4336, C07C10352

Patent

active

044838506

ABSTRACT:
N-Terminal substituted oligopeptides are disclosed. The compounds are angiotensin converting enzyme inhibitors useful as antihypertensives.

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patent: 4385180 (1983-05-01), Kim et al.
D. W. Cushman, et al., Biochemistry, 16, 5484, (1977).
Y. Piquilloud, et al., Biochem. Biophys. Acta, 206, 136 (1970).
Weeks, et al., Proc. Soc. Exp. Biol. Med., 104, 636, (1969).
Koletsky, et al., Proc. Soc. Exp. Biol. Med., 125, 96, (1967).

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