N.sup.2 -alkoxynaphthylsulfonyl-L-argininamides and the pharmace

Details N.sup.2 -alkoxynaphthylsulfonyl-L-argininamides and the pharmace N.sup.2 -alkoxynaphthylsulfonyl-L-argininamides and the pharmace

1977-01-19

1978-02-14

Phillips, Delbert R.

Drug, bio-affecting and body treating compositions

Immunoglobulin, antiserum, antibody, or antibody fragment,...

Reduced antigenicity, reduced ability to bind complement, or...

2601125R, A61K 3700, C07C10352

Patent

active

040738922

ABSTRACT:
N.sup.2 -alkoxynaphthylsulfonyl-L-argininamides and the pharmaceutically acceptable salts thereof have been found to be effective as pharmaceutical agents for the inhibition and suppression of thrombosis in mammals, and are prepared by reacting an N.sup.2 -alkoxynaphthylsulfonyl-L-arginyl halide with an N-substituted amino acid or an ester thereof.

REFERENCES:
patent: 3131174 (1964-04-01), Schwyer
patent: 4018913 (1977-04-01), Okamoto et al.
patent: 4018915 (1977-04-01), Okamoto et al.

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