N-sulfonylindoline derivatives, their preparation and the pharma

Details N-sulfonylindoline derivatives, their preparation and the pharma N-sulfonylindoline derivatives, their preparation and the pharma

1994-05-10

1995-03-14

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514414, 514369, 548483, 548484, 548485, 548490, 548491, 548181, 548182, 548183, 548468, 544 62, 544255, 544144, 544373, 5442282, 5442352, 546201, 546273, 540597, A61K 3140, C07D20910, C07D41306, C07D41706

Patent

active

053978013

ABSTRACT:
The invention relates to N-sulfonyl derivatives of formulae (I) and (I)' ##STR1## to their preparation, and to pharmaceutical compositions in which they are present. The compounds of formulae (I) and (I)' have an affinity for the vasopressin and ocytocin receptors.

REFERENCES:
patent: 3838167 (1974-09-01), Jones
patent: 4479963 (1984-10-01), Gruenfeld
CA 116:214341z Preparation . . . Ligands. Wagnon et al., p. 728, 1992.
CA 119:139091z Preparation . . . Antagonists. Wagnon et al., p. 864, 1993.

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