Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1993-10-18
1997-01-28
Wityshyn, Michael G.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514822, 530331, A61K 3700, A61K 3702, C07K 508
Patent
active
055978045
ABSTRACT:
The present invention is directed to N-sulfonyl arginine alpha-keto-amide derivatives, their pharmaceutically acceptable salts and compositions thereof which are useful as antithrombotic agents in mammals and also the use of these compounds as antithrombotic agents. Also, disclosed are methods of using these inhibitors in their various embodiments as therapeutic agents for disease states characterized by disorders of the blood coagulation process. Further disclosed are compounds useful as intermediates in the preparation of these compounds.
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Abelman Matthew M.
Miller Todd A.
Vlasuk George P.
Webb Thomas R.
Corvas International Inc.
Weber Jon P.
Wityshyn Michael G.
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