N-Sugar compounds, compositions and uses thereof

Drug – bio-affecting and body treating compositions – Conjugate or complex of monoclonal or polyclonal antibody,... – Conjugated via claimed linking group – bond – chelating agent,...

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536 22, 536 23, A61K 3170, C07H 1900, C07H 1700, C07H 502

Patent

active

043672264

ABSTRACT:
Novel, water-soluble antimicrobial compounds are provided which contain a sugar moiety linked to a nitrogen atom of substituted thiourea or a thiazole. The compounds have the general formula: ##STR1## and the pharmaceutically acceptable salts thereof wherein Su is a sugar moiety, i.e., mono- or polysaccharide and preferably glucosyl or acylated (i.e. C.sub.2 to C.sub.6 alkanoyl e.g. acetyl, propionyl, butyroyl etc. or aroyl e.g. benzoyl or C.sub.1 to C.sub.4 alkyl or alkoxy substituted benzoyl) ribosyl; and

REFERENCES:
patent: 4066750 (1978-01-01), Smith et al.
patent: 4109078 (1978-08-01), Vorbruggen et al.
Bannister, B., J. Antibiotics, vol. 25, pp. 377-386, 1972.

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