N-(substituted thienyl)-N'-(substituted piperazinyl)-ureas

Details N-(substituted thienyl)-N'-(substituted piperazinyl)-ureas N-(substituted thienyl)-N'-(substituted piperazinyl)-ureas

1987-01-21

1987-11-17

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544250, 544278, 544376, C07D40912

Patent

active

047075503

ABSTRACT:
The synthesis of thienopyrimidine-2,4-dione derivatives and their urea intermediates is described. The novel urea intermediates and thienopyrimidine-2,4-dione derivatives are general vasodilating agents and anti-hypertensive agents. The compounds are useful as cardiovascular agents.

REFERENCES:
patent: 3855243 (1974-12-01), Ruschig et al.
patent: 4123529 (1978-10-01), Verge et al.
patent: 4613596 (1986-09-01), Moroni

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