Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1982-10-25
1985-04-30
Brust, Joseph Paul
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
548527, 548572, 514428, A61K 3140, C07D20708
Patent
active
045144141
ABSTRACT:
N-Substituted pyrrolidineacetic acids and their esters, useful as inhibitors of GABA uptake, are prepared by reacting an appropriate N-alkylating derivative with an esters of an N-unsubstituted pyrrolidineacetic acid followed by hydrolysis of the ester.
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Sam, et al., J.A.C.S., 81, (1959), pp. 710-713.
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Rajsner, et al., C.A. 59:13936f, (1963).
Bondinell William E.
Lafferty John J.
Zirkle Charles L.
Brust Joseph Paul
Foggio Richard D.
Keps Joan S.
Lourie Alan D.
SmithKline Beckman Corporation
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