N-Substituted pyridinones having histamine H.sub.2 -antagonist a

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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544320, 544332, 544333, 546261, 546284, 546304, 546339, 548138, 548182, 548213, 548351, 548352, 548348, A61K 31505, C07D23902

Patent

active

045406995

ABSTRACT:
This invention relates to N-substituted pyridinone compounds which have histamine H.sub.2 -antagonist activity. A specific compound of this invention is 2-[2-(5-methyl-4-imidazolylmethylthio)ethylamino]-5-(1-methyl-2-oxopyridin -4-ylmethyl)pyrimidin-4-one.

REFERENCES:
patent: 3932644 (1976-01-01), Durant et al.
patent: 3980781 (1976-09-01), Snell et al.
Alfred Burger, Medicinal Chem., 2nd edition, p. 42.

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