N-(substituted phenyl) tetrazol-5-yl carboxamides and anti-aller

Details N-(substituted phenyl) tetrazol-5-yl carboxamides and anti-aller N-(substituted phenyl) tetrazol-5-yl carboxamides and anti-aller

1987-06-01

1989-02-28

Springer, David B.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

548251, 548252, C07D25704, A61K 3141

Patent

active

048086045

ABSTRACT:
Novel 4-acylresorcinol ethers of the formula ##STR1## in which R.sub.1 is lower alkyl, alk is a hydroxyalkylene radical which can be interrupted by oxygen and R.sub.2 is 5-tetrazolyl, it being possible for the ring A to be additionally substituted by a lower alkyl, lower alkenyl, lower alkynyl, lower alkoxy and/or halogen and for the ring B to be additionally substituted by lower alkyl, lower alkanoyl, lower alkoxy, lower alkoxycarbonyl, carboxyl, cyano, carbamyl, halogen and/or trifluoromethyl, and salts thereof have antiallergic properties and can be used as active compounds for medicaments. They are prepared by methods known as per se.

REFERENCES:
patent: 3966965 (1976-06-01), Sellstedt
patent: 4119783 (1978-10-01), Hall et al.
patent: 4159278 (1979-06-01), Hall et al.
patent: 4442115 (1984-04-01), Ramsden et al.
patent: 4448729 (1984-05-01), Klaubert et al.
patent: 4507498 (1985-03-01), Carson

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