N-substituted nonaryl-heterocyclo amidyl NMDA/NR2B Antagonists

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C514S222200, C514S228800, C514S250000, C514S262100, C514S263220, C514S252030, C514S255050, C514S256000, C514S314000, C514S315000, C514S330000, C514S336000, C514S351000, C514S354000, C514S357000, C514S365000, C546S169000, C546S180000, C546S193000, C546S194000, C546S198000, C546S199000, C546S201000, C546S207000, C546S208000, C546S209000, C546S210000, C546S211000, C546S212000, C546S213000, C546S224000, C546S226000, C546S229000, C546S231000, C546S236000, C546S237000, C544S238000, C544S262000, C544S277000, C544S

Reexamination Certificate

active

10114685

ABSTRACT:
Compounds represented by Formula (I):or pharmaceutically acceptable salts thereof, are effective as NMDA NR2B antagonists useful for relieving pain.

REFERENCES:
patent: 5306723 (1994-04-01), Chenard et al.
patent: 5436255 (1995-07-01), Butler et al.
patent: 5648368 (1997-07-01), Egertson et al.
patent: 6197769 (2001-03-01), Alisi et al.
patent: 6303637 (2001-10-01), Bao et al.
patent: 6706740 (2004-03-01), Ricks et al.
patent: 3702755 (1988-08-01), None
patent: 441506 (1991-08-01), None
patent: 532456 (1993-03-01), None
patent: 787493 (1997-08-01), None
patent: 846683 (1998-06-01), None
patent: WO91/17156 (1991-11-01), None
patent: WO91/19709 (1991-12-01), None
patent: 9203415 (1992-03-01), None
patent: WO92/18502 (1992-10-01), None
patent: WO93/02052 (1993-02-01), None
patent: WO94/20062 (1994-02-01), None
patent: WO94/14776 (1994-07-01), None
patent: WO94/21615 (1994-09-01), None
patent: WO96/02250 (1996-02-01), None
patent: WO96/10035 (1996-04-01), None
patent: WO96/34856 (1996-11-01), None
patent: WO96/37226 (1996-11-01), None
patent: WO97/28139 (1997-08-01), None
patent: WO97/28141 (1997-08-01), None
patent: WO97/45119 (1997-12-01), None
patent: WO98/04913 (1998-02-01), None
patent: WO98/05336 (1998-02-01), None
patent: WO98/31669 (1998-07-01), None
patent: WO98/31677 (1998-07-01), None
patent: WO98/46589 (1998-10-01), None
patent: WO 00/00197 (2000-01-01), None
patent: WO 00/08015 (2000-02-01), None
patent: WO 00/11002 (2000-03-01), None
patent: WO 00/25786 (2000-05-01), None
patent: WO 00 71518 (2000-11-01), None
patent: 100207 (2001-01-01), None
Richter et al,PubMed Abstract 12498913, also cited as Eur.J.Pharmacol. 458/1-2,107-10(2003).
Kuraishi et al,PubMed Abstract 113338373,also cited as Nippon Yakurigaku Zasshi,117/4,248-54(2001).
Wright et al,PubMed Abstract 10522697, also cited as Bioorg. Med. Chem. Lett.,9/19,2815-8(1999).
Chabrier et al, PubMed Abstract 10442086, also cited as Cell Mol. Life Sci.,55/8-9,1029-35(1999).
Laurie et al,PubMed Abstract 7528680, also cited as Eur. J. Pharmacol. 268/3,335-45(1994).
Alisi et al. Chemical Abstracts, vol. 129:316219, 1998.
Ricks et al., Chemical Abstracts, vol. 134:131431, 2001.
T. Ishii, et al., J.Biol. Chem., 268:2836-2843(1993).
M.B. Max, et al., Clin. Neuropharmacology, 18:360-368(1995).
D.J. Knox, et al., Anaesth. Intens. Care, 23:620-622(1995).
P.K. Eide, et al., Pain, 61:221-228(1995).
J.D. Kristensen, et al., Pain, 51:249-253(1992).
K. Taniguchi, et al., Brit. J. Pharmacology, 122:809-812(1997).
R. Jain, et al., Tetrahedron, 54:3235-3242(1998).
W. Danysz, et al., Pharmacological Rev., 50:597-664(1998).
R.D. Clark, et al., J. Med. Chem., 26:855-861(1983).
A. Dickenson, TIPS, 11:307-309(1990).
A. Wenzel, et al., Neurochemistry, 7:45-48(1995).
J.N.C. Kew, et al., Brit. J. Pharmacology, 123:463-472(1998).
Electronic Database Printout, CAPLUS 1999:617466,218th ACS Nat. Mtg., N. Orleans, Aug. 22-26, 1999.
Z.-L. Zhou, et al., J. Med. Chem., 42:2993-3000(1999).
S. Boyce, et al., Neuropharmacology, 38:611-623(1999).
D.J. Laurie, et al., Mol. Brain Res., 51:23-32(1997).
Electronic Database Printout CAPLUS STN No. 98:191287 (1983).
Electronic Database Printout CAPLUS STN No. 135:298146 (2001).

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