Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1977-10-25
1979-03-13
Schwartz, Gerald A.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
546112, 260239BA, 544159, 544124, 544 85, 26050114, 424244, 424267, 42424852, 4242485, 424326, 542416, C07C12300
Patent
active
041442717
ABSTRACT:
N-substituted mercaptomethylacetamidines are prepared, and are useful as immunoregulants for correcting an imbalance of immune homeostasis, particularly, as immunostimulants in the treatment of autoimmune and immune deficient diseases and disorders.
REFERENCES:
patent: 3732305 (1973-05-01), Bauer
patent: 3775478 (1973-11-01), Bockstahler
Journal of Medicinal Chemistry, vol. 15, pp. 1313-1321 (1972) (Bauer et al.).
Bauer et al., Journal of Medicinal Chemistry, vol. 7, pp. 766-768 (1964).
Conway et al., Journal of Pharmaceutical Science, vol. 57, pp. 455-459 (1968).
Bauer et al., J. Organic Chemistry, vol. 27, pp. 4382-4385 (1962).
Parulkar et al., J. Heterocyclic Chem. (1966), pp. 472-475.
Dorn Conrad P.
Jones Howard
Merck & Co. , Inc.
Monaco Mario A.
Schwartz Gerald A.
Speer Raymond M.
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