N-substituted imidazoles as aromatase inhibitors

Details N-substituted imidazoles as aromatase inhibitors N-substituted imidazoles as aromatase inhibitors

1989-03-31

1990-04-10

Schwartz, Richard A.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514397, 514399, 546210, 548335, 548336, A61K 31445, A61K 31415, C07D23360, C07D23361

Patent

active

049161440

ABSTRACT:
The invention relates to N-substituted imidazoles of the formula, ##STR1## processes for their production as well as their use in pharmaceutical agents. The compounds according to the invention have aromatase-inhibiting properties and are suitable for therapy of estrogen-caused diseases.

REFERENCES:
Strehlke et al., Eur. J. Med. Chem.-Chimica Therapeutica, May-Jun., 1979, 14, No. 3, pp. 231-237.

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