N-substituted glycine derivatives as enzyme inhibitors

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues – Tripeptides – e.g. – tripeptide thyroliberin – etc.

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

530330, C07K 500, C07K 400

Patent

active

060254726

ABSTRACT:
The present invention discloses peptide aldehydes which are potent inhibitors of factor Xa, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.

REFERENCES:
patent: 4883863 (1989-11-01), Abe et al.
patent: 5380713 (1995-01-01), Balasubramanian et al.
Szelke et al., "Synthetic inhibitors of tissue kallikrein: effects in vivo in a model of allergic inflammation," Brazilian J. Med. Biol. Res. 27:1943-1947 (1994).

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

N-substituted glycine derivatives as enzyme inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-substituted glycine derivatives as enzyme inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-substituted glycine derivatives as enzyme inhibitors will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1906967

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.