N-substituted glycine derivatives as enzyme inhibitors

Details N-substituted glycine derivatives as enzyme inhibitors N-substituted glycine derivatives as enzyme inhibitors

1995-06-07

2000-02-15

Celsa, Bennett

Chemistry: natural resins or derivatives; peptides or proteins;

Peptides of 3 to 100 amino acid residues

Tripeptides, e.g., tripeptide thyroliberin , etc.

530330, C07K 500, C07K 400

Patent

active

060254726

ABSTRACT:
The present invention discloses peptide aldehydes which are potent inhibitors of factor Xa, their pharmaceutically acceptable salts, pharmaceutically acceptable compositions thereof, and methods of using them as therapeutic agents for disease states in mammals characterized by abnormal thrombosis.

REFERENCES:
patent: 4883863 (1989-11-01), Abe et al.
patent: 5380713 (1995-01-01), Balasubramanian et al.
Szelke et al., "Synthetic inhibitors of tissue kallikrein: effects in vivo in a model of allergic inflammation," Brazilian J. Med. Biol. Res. 27:1943-1947 (1994).

Affiliated with

Also associated with

Rating

N-substituted glycine derivatives as enzyme inhibitors does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N-substituted glycine derivatives as enzyme inhibitors, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N-substituted glycine derivatives as enzyme inhibitors will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1906967