N-substituted azaheterocyclic carboxylic acids and esters thereo

Details N-substituted azaheterocyclic carboxylic acids and esters thereo N-substituted azaheterocyclic carboxylic acids and esters thereo

1995-05-18

1997-11-18

Shah, Mukund J.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514220, 514183, 514217, 5142298, 5142255, 514297, 514324, 514325, 540550, 540495, 540479, 540592, 540522, 544102, 544 31, 546103, 546102, 546202, 546203, 546204, C07D40106, C07D40306, C07D41306, A61K 3155

Patent

active

056887884

ABSTRACT:
The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.

REFERENCES:
patent: 2957870 (1960-10-01), Cusic et al.
patent: 3069432 (1962-12-01), Yale et al.
patent: 3177211 (1965-04-01), Zenitz et al.
patent: 3316249 (1967-04-01), Hanze et al.
patent: 5420123 (1995-05-01), Murugesan
Andersen et al., J. Med Cem., vol. 36, pp. 1716-1725, 1993.
Nakanishi et a., J. Med Cem., vol. 13, No. 4, pp. 644-648, 1979.

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