N-substituted azaheterocyclic carboxylic acids and esters thereo

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546102, 546103, 546202, 546203, 546204, 514220, 514183, 514217, 5142298, 540550, 540495, 540479, 540592, 540522, 544102, 544 31, C07D41306, A61K 31535

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active

056936494

ABSTRACT:
The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain forms part of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.

REFERENCES:
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patent: 3177211 (1965-04-01), Zenitz et al.
patent: 5296602 (1994-03-01), Su et al.
Andersen et al., J. Med Cem., vol. 36, pp. 1716-1725, 1993.
Nakanishi et a., J. Med Cem., vol. 13, No. 4, pp. 644-648, 1979.

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