Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1995-10-18
1998-08-18
Berch, Mark L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
5142255, 5142298, 544 46, 544102, A61K 31645, C07D41306, C07D40106, C07D40306
Patent
active
057958882
ABSTRACT:
The present invention relates to novel N-substituted azaheterocyclic carboxylic acids and esters thereof in which a substituted alkyl chain of the N-substituent or salts thereof, to methods for their preparation, to compositions containing them, and to their use for the clinical treatment of painful, hyperalgesic and/or inflammatory conditions in which C-fibers play a pathophysiological role by eliciting neurogenic pain or inflammation.
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Andersen et al., J. Med. Chem., vol. 36, pp. 1716-1725, 1993.
Nakanishi et al., J. Med. Chem., vol. 13, No. 4, pp. 644-648, 1979.
Andersen Henrik Sune
Andersen Knud Erik
Gr.o slashed.nvald Frederik Christian
J.o slashed.rgensen Tine Krogh
Olsen Uffe Bang
Berch Mark L.
Lambiris Elias J.
Novo Nordisk A S
Zelson Steve T.
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