N-substituted amides

Details N-substituted amides N-substituted amides

1991-04-16

1993-06-22

Lee, Lester L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Peptide containing doai

514 17, 530330, A61K 3702, C07K 510, C07K 706

Patent

active

052216659

ABSTRACT:
N-substituted amides which inhibit hydrolysis of elastin, are described, which compounds are tri-and di- fluoromethyl ketone amide and non-naturally occurring n-substituted amino acids derivatives.

REFERENCES:
patent: 4873221 (1989-10-01), Trainor
patent: 4880780 (1989-11-01), Trainor et al.
patent: 4910190 (1990-03-01), Bergeson et al.
patent: 4923890 (1990-05-01), Trainor et al.
Stein et al., "Mechanism of Slow Binding Inhibition of HLE by Trifluoromethyl Ketones", Biochem. (1987) 26, pp. 2682-2689.

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