Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1990-04-27
1993-03-30
Springer, David B.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
546205, 546174, C07D21128, A61K 31445
Patent
active
051984490
ABSTRACT:
Novel compounds of the formula below wherein W is azetidine, pyrrolidine or piperidine, Q is a straight chain hydrocarbon radical of 1-4 carbons and may contain a double bond, and ##STR1## Ar is phenyl, pyridinyl or pyrimidinyl, a process for their preparation, and novel intermediates are disclosed. The novel compounds and the pharmaceutical compositions of this invention are useful in the treatment of hypertension, arrhythmias and angina.
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patent: 3576810 (1971-04-01), Duncan
patent: 4777176 (1988-10-01), Worthington
E. K. Orlova et al., Khim.-Farm. Zh. 1979, 13(1), 47-51 (Russ) CA90:168416x.
Hesley et al., J. Med. Chem., 11, 472-475 (1968).
Helsley et al., J. Med. Chem., 12, 1098-1100 (1969).
Duncan et al., J. Med. Chem., 13, 1-6 (1970).
A. H. Robins Company Incorporated
Patton Walter
Springer David B.
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