Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1997-06-26
1998-12-08
Lilling, Herbert J.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
435171, 4352554, 435921, C12P 1712
Patent
active
058467912
ABSTRACT:
Asymmetric bioreduction of a ketone substrate with yeast produces the corresponding (R)-alcohol of structure: ##STR1## a key intermediate in the synthesis of a .beta..sub.3 -agonist of structure ##STR2##
REFERENCES:
patent: 5561142 (1996-10-01), Fisher
Chartrain Michel M.
Chung John Y. L.
Roberge Christopher
Lilling Herbert J.
Merck & Co. , Inc.
Rose David L.
Yang Mollie M.
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