N-(R)-(2-hydroxy-2-pyridine-3-yl-ethyl)-2-(4-nitro-phenyl)-aceta

Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...

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435171, 4352554, 435921, C12P 1712

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active

058467912

ABSTRACT:
Asymmetric bioreduction of a ketone substrate with yeast produces the corresponding (R)-alcohol of structure: ##STR1## a key intermediate in the synthesis of a .beta..sub.3 -agonist of structure ##STR2##

REFERENCES:
patent: 5561142 (1996-10-01), Fisher

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