N-pyrimidinyl-N-dialkylaminoalkyl ureas

Details N-pyrimidinyl-N-dialkylaminoalkyl ureas N-pyrimidinyl-N-dialkylaminoalkyl ureas

1977-02-17

1979-03-13

Coughlan,, Jr.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

424249, 424250, 544182, 544224, 544320, 544321, 544323, 544329, 544330, 544332, 544336, 544409, A61K 31505, C07D23942

Patent

active

041443381

ABSTRACT:
Organic chemical compounds based upon the urea molecule are disclosed which have potent gastric secretion inhibitory properties. The urea is substituted with a 6 membered heterocyclic substituent containing 2 or 3 heteroatoms, and also with a substituted amino alkyl group. Further substitution is also possible. The compounds have profound effects on the inhibition of gastric secretions in the gastro-intestinal tract, and compositions for such uses are also disclosed.

REFERENCES:
patent: 3705159 (1972-12-01), Schneider et al.
patent: 3759921 (1973-09-01), Paget
patent: 3950537 (1976-04-01), DeBenneville et al.
patent: 4008235 (1977-02-01), Lesher et al.

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