N-phenyl-2-pyrimidine-amine derivatives

Details N-phenyl-2-pyrimidine-amine derivatives N-phenyl-2-pyrimidine-amine derivatives

2007-12-25

2007-12-25

Rao, Deepak (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S252180, C514S275000, C544S122000, C544S295000, C544S330000, C544S331000

Reexamination Certificate

active

11448649

ABSTRACT:
The invention relates to N-phenyl-2-pyrimidine-amine derivatives of formula Iwherein the substituents are defined as indicated in the description, to processes for the preparation thereof, to medicaments comprising those compounds, and to the use thereof in the preparation of pharmaceutical compositions for the therapeutic treatment of warm-blooded animals, including humans.

REFERENCES:
patent: 5521184 (1996-05-01), Zimmermann
patent: 7081532 (2006-07-01), Buerger et al.
patent: 0 564 409 (1993-10-01), None
patent: WO 00/78731 (2000-12-01), None
Zimmerman et al., “Phenylamino-Pyrimidine (PAP)—Derivatives: A New Class of Potent and Highly Selective PDGF-Receptor Autophosphorylation Inhibitors”,Bioorg. Med. Chem. Lett., vol. 6, No. 11, pp. 1221-1226 (1996).
Simone, Oncology: INtroduction, Cecil Textbook of Medicine, 20thEdition, vol. 1, pp. 1004-1010 (1996).
Traxler, Protein tyrosine kinase inhibitors in cancer treatment, Exp. Opin. Ther. Patents, 7(6):571-588, (1997).
Tucker et al., Optimizing drug development: Strategies to asess drug metabolism/transporter interaction potential—toward a consensus. Clinical Pharmacology Therapeutics, vol. 70(3), pp. 103-114 (Aug. 2001).

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