Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1997-02-28
1998-12-08
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
514314, 514316, 514318, 514323, 514320, 514317, 514326, 514332, 514331, 514337, 514336, 514354, 514423, 546186, 546193, 546205, 546168, 540597, 540602, 540603, 540607, 540608, 518527, 518517, 518518, A61K 3147, A61K 31445, C07D21102
Patent
active
058469796
ABSTRACT:
This invention relates to neurotrophic low molecular weight, small molecule N-oxides of heterocyclic esters, amides, thioesters, and ketones having an affinity for FKBP-type immunophilins, and their use as inhibitors of the enzyme activity associated with immunophilin proteins, particularly peptidyl-prolyl isomerase, or rotamase, enzyme activity.
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Burak Eric S.
Hamilton Gregory S.
Steiner Joseph P.
GPI Nil Holdings Inc.
Juneau Todd L.
M. Mach D. Margaret
Nath Gary M.
Rotman Alan L.
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