N-[.omega.-(4'-(3"-indolyl)-piperidino)-alkyl]-benzamides

Details N-[.omega.-(4'-(3"-indolyl)-piperidino)-alkyl]-benzamides N-[.omega.-(4'-(3"-indolyl)-piperidino)-alkyl]-benzamides

1975-01-22

1976-04-13

Trousof, Natalie

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Parasitic organism or component thereof or substance...

26029361, C07D40104

Patent

active

039505278

ABSTRACT:
N-[.omega.-(4'-(3"-indolyl)-piperidino)-alkyl]-benzamides of the formula ##SPC1##
Wherein R is selected from the group consisting of hydrogen and alkoxy of 1 to 3 carbon atoms, R.sub.1 and R.sub.2 are individually selected from the group consisting of hydrogen and alkyl of 1 to 3 carbon atoms, n is 2 or 3, X is selected from the group consisting of hydrogen and alkoxy of 1 to 3 carbon atoms, X.sub.1 is selected from the group consisting of hydrogen, fluorine, chlorine, bromine, --NH.sub.2 and ##EQU1## and X.sub.2 is selected from the group consisting of hydrogen, chlorine and sulfamoyl and their non-toxic, pharmaceutically acceptable acid addition salts having neurosedative properties and their preparation.

REFERENCES:
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Archibald et al., J. Med. Chem. 1971, Vol. 14, pp. 1054-1059.
Bruce, Chem. Abst. 1974, Vol. 80, No. 95560w.
Eichele et al., Chem. Abst. 1971, Vol. 74, No. 21674r.
Jucker et al., Chem. Abst., 1969, Vol. 71, No. 81413c.
Newberry et al., Chem. Abst., 1972, Vol. 77, No. 151956g.
Richter et al., Chem. Abst., 1963, Vol. 58, Cols. 10134.
Tozaburo et al., Chem. Abst., 1960, Vol. 54, Cols. 19576-19577.

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