N-naphthoylglycine derivatives

Details N-naphthoylglycine derivatives N-naphthoylglycine derivatives

1985-07-17

1986-07-15

Shippen, Michael L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

560 10, 562427, C07C15305, A61K 31195

Patent

active

046007245

ABSTRACT:
Herein disclosed are N-naphthoylglycine derivatives having aldose reductase inhibiting activity. The derivatives are useful for treating diabetic complications.

REFERENCES:
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patent: 4391816 (1983-07-01), Sestanj
D. Dvornik et al., Science, 182, 1146 (1973).
M. J. Peterson et al., Metabolism, 28 (Suppl. 1), 456(1979).
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V. I. Cohen et al., Eur. J. Med. Chem., 5, 480(1976); see also Chem Asbtr., 86, 189582f (1977).
J. Voss and W. Walter, Justus Leibigs Ann. Chem., 716, 209 (1968); see also Chem. Abstr., 70, 11306a (1969).
Chem. Abstr., 61, 4333f(1964) for E. Cioranescu et al., Rev. Chim. Acad. Rep. Populaire Roumaine, 7 (2), 755(1962).

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