N,N'-disubstituted guanidines containing a carboxyl or a tetrazo

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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Details

548252, 548254, 564161, 564163, 426534, 426535, 426536, 426537, 514312, A61K 3141, C07D25704

Patent

active

049007408

ABSTRACT:
N,N'-disubstituted guanidines containing a tetrazolyl or glycine moiety are provided as high potency sweetening agents.

REFERENCES:
patent: 3492131 (1970-01-01), Schlatter
patent: 3535336 (1970-10-01), Kornfeld
patent: 3615700 (1971-10-01), Kornfeld
patent: 3899592 (1975-08-01), Suarez et al.
patent: 4426521 (1984-01-01), Tanaka et al.
patent: 4645678 (1987-02-01), Nofre et al.
patent: 4673582 (1987-06-01), Nofre et al.
patent: 4680300 (1987-07-01), Nelson et al.
Yuki and Inoue, The Reaction of Urea, Thiourea and S-Ethylisothiourea with Methyl Acrylate, Nippon Kagaku Kaishi, 1974, (11), 2140-43, (Translation), (Chemical Abstracts, 140061p, vol. 82, (1975)).
Lipinski, Bioisosterism in Drug Design, Annual Reports in Medicinal Chemistry, 21, 283-291, (1986).
Burger, A Guide to the Chemical Basis of Drug Design, History of Medicinal Chemistry, 28-30, 46, 84-87, (1983).
Thornber, Isosterism and Molecular Modification in Drug Design, 563-580, (1979).
Chemische Berichter, vol. 94, No. 7, 1961, pp. 1814-1824, Weinheim, D. E.; F. Micheel et al., (with translation).
Tsang et al., Peptide Sweeteners, 6, Structural Studies on the C-Terminal Amino Acid of L-Aspartyl Dipeptide Sweeteners, American Chemical Society, Jan. 3, 1984, 6 pages.
Ariyoshi et al., The Structure-Taste Relationships of the Dipeptide Esters Composed of L-Aspartic Acid and B-Hydroxy Amino Acids, Bulletin of the Chemical Society of Japan, 02/1974, pp. 326-330.
Tinti et al., Sweet Taste Receptor, Naturwissenschaften, 67, Jan. 2, 1980, pp. 193-194.
Tinti et al., Studies on Sweeteners Requiring the Simultaneous Presence of Both the NO.sub.2 /CN and COO.sup.- Groups, Naturwissenschaften, 68, Dec., 1981, p. 143.
Miller et al., A Facile Conversion of Amino Acids to Guanidino Acids, Communications, Sep. 1986, 777-779.
Kawashima, J. Agricultural and Food Chem., vol. 28, No. 6, pp. 1338-1340, (1980).

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