N,N-Disubstituted 2,3-diphenylallylamines

Details N,N-Disubstituted 2,3-diphenylallylamines N,N-Disubstituted 2,3-diphenylallylamines

1975-07-25

1977-03-22

Demers, Arthur P.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260240CA, 260240R, 260562P, 2605676M, 2605705R, 424251, 424258, 424263, 424267, 424274, 424324, 424329, 424330, C07D23906, C07C 8729

Patent

active

040136434

ABSTRACT:
The above-captioned compounds are produced from optionally substituted benzoin compounds by sequential reactions with trizincbismethylene dibromide, phosphorous trichloride and an appropriately substituted amine. The instant compounds are valuable as pharmacological agents as is evidenced by their anti-microbial, anti-arrhythmic, pepsin-inhibitory and anti-hypertensive activity.

REFERENCES:
patent: 2485662 (1949-10-01), Rohrmann
patent: 3422153 (1969-01-01), Mills et al.
Jones et al. J. Med. Chem. 14 (1971) pp. 161-164.
Shapiro Chem. Abst. 46 3056(d).
Fuks et al. Chem Ber. 103 (1970) pp. 564, 565, 571.

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