N,N-dimethyldiatrizoic acid and its conjugates as hepatobiliary

Details N,N-dimethyldiatrizoic acid and its conjugates as hepatobiliary N,N-dimethyldiatrizoic acid and its conjugates as hepatobiliary

1999-03-22

2000-04-18

Hollinden, Gary E.

Drug, bio-affecting and body treating compositions

In vivo diagnosis or in vivo testing

X-ray contrast imaging agent

A61B 813

Patent

active

060512105

ABSTRACT:
Compounds having formulae I, II or III, or pharmaceutically acceptable salts thereof, ##STR1## wherein ##STR2## R.sub.1, R.sub.2, R.sub.3, R.sub.4, R.sub.5, R.sub.6, R.sub.7 and R.sub.8 are the same or different and are hydrogen, alkyl, substituted or unsubstituted cycloalkyl, substituted or unsubstituted aralkyl, substituted or unsubstituted aryl, haloalkyl, hydroxyalkyl, alkoxyalkyl, carboxyalkyl or carboxamido alkyl with the proviso that in formula I R.sub.2 and R.sub.3 cannot be methyl; and

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patent: 4735795 (1988-04-01), Robinson et al.
Haugen et al., Chemical Abstracts 60:15692(c), 1963.

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