Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai
Patent
1985-02-28
1987-04-21
Phillips, Delbert R.
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Peptide containing doai
514 13, 530324, 530325, 530326, A61K 3743, C07K 710, C07K 708
Patent
active
046596933
ABSTRACT:
Peptides which promote the release of growth hormone by the pituitary gland or which inhibit the release of growth hormone by growth hormone releasing factor and which have an N,N'-dialkyl substituted guanidino amino acyl residue at position 1 or 2 are disclosed herein.
REFERENCES:
patent: 3773919 (1973-11-01), Boswell et al.
patent: 4118483 (1978-10-01), Konig et al.
patent: 4218474 (1980-08-01), Barnish et al.
Ling et al., 65th Annual Endocrine Society Meeting, 295, 154, 1983.
Rivier et al., 8th American Peptide Symposium, Tucson, Arizona, May 22-27, p. 237, 1983.
Ech et al., Biochemical and Biophysical Research Communications, 117, 772-779 (1983).
Guillemin et al., "Science, 218, 585-587 (1982).
Journal of Exper. Zoology 231:161-63 (1984).
Moore Annette M.
Moran Tom M.
Phillips Delbert R.
Syntex (U.S.A.) Inc.
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