Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1992-05-19
1994-03-08
Bernhardt, Emily
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514 80, 514217, 5142278, 5142282, 5142328, 5142358, 514252, 514253, 514255, 540479, 540591, 544 60, 544121, 544337, 544357, 544359, 544361, 544372, 544380, 544387, 544388, 548542, 562844, 564218, 564305, A61K 31675, A61K 31495, C07D24104, C07F 96509
Patent
active
052927261
ABSTRACT:
Diacylpiperazines of general structure ##STR1## are: angiotensin II (A-II) antagonists selective for the type 2 (AT.sub.2) subtype useful in the treatment of cerebrovascular, cognitive, and CNS disorders; tachykinin receptor antagonists useful in the treatment of inflammatory diseases and pain or migraine; and calcium channel blockers useful in the treatment of cardiovascular conditions such as angina, hypertension or ischemia.
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Ashton Wallace T.
Dorn Conrad P.
Greenlee William J.
Maccoss Malcolm
Mills Sander G.
Bernhardt Emily
Caruso Charles M.
Merck & Co. , Inc.
Thies J. Eric
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