N,N'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine

Details N,N'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine N,N'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine

1988-11-10

1990-10-23

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

540217, 540222, 540227, 540316, 544229, 544385, C07D40302

Patent

active

049653580

ABSTRACT:
A new compound called N,N'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine of Formula I ##STR1## A process for the preparation thereof based on the reaction of 4-ethyl-2,3-dioxo-piperazine or a trimethylsilyl derivative thereof with carbonyl chloride or a derivative thereof.
The use of the compound of Formula I as an intermediate in the preparation of compounds of Formula II ##STR2## where R is a radical, substituted in alpha position, of a molecule of an acid selected from the group formed by phenylacetic acid, p-hydroxy phenylacetic acid, a 6-(phenylacetamido)-penicillanic acid and a 7-(phenylacetamido)-cephalosporanic acid.

REFERENCES:
patent: 3763091 (1973-10-01), Crescenzi et al.
patent: 4110327 (1978-08-01), Saikawa et al.
patent: 4110328 (1978-08-01), Diamond
patent: 4200744 (1989-04-01), Saikawa et al.
patent: 4436921 (1984-03-01), Hori et al.
Derwent Abstract, Belgium 837682 (1976).
Derwent Abstract, Japan 52-19685 (1977).
Derwent Abstract, Europe 131174 (1985).
Derwent Abstract, Japan 52106883 (1977).
Derwent Abstract, Germany 26800880 (1977).
Derwent Abstract, Germany 2702552 (1977).
Chem. Abst., 104:148590d, Yao et al., Synthetic Studies of Piperacillin, 1985.

Affiliated with

Also associated with

Rating

N,N'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with N,N'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and N,N'-carbonyl-bis-(4-ethyl-2,3-dioxo)-piperazine will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-767801