N,N'-Bridged-bis[N,N'substituted-2-hydroxy alkaneammonium] salts

Details N,N'-Bridged-bis[N,N'substituted-2-hydroxy alkaneammonium] salts N,N'-Bridged-bis[N,N'substituted-2-hydroxy alkaneammonium] salts

1977-09-15

1978-10-10

Thomas, Jr., James O.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07C 8730, A61K 3114

Patent

active

041196686

ABSTRACT:
N,N'-Bridged-bis[(O and/or N-substituted)-2-alkyl-2-hydroxyethylamines] of the formula ##STR1## are prepared by condensing an epoxide of the formula ##STR2## and a diamine of the formula R'NH-X-NHR'. The products and dicarbanilates, acid-addition salts, N,N'-dioxides and N,N'-diammonium quaternary salts derived therefrom have antibacterial activity in vitro and are useful as antibacterial agents.

REFERENCES:
patent: 3370048 (1968-02-01), Reynolds
patent: 4024311 (1977-05-01), MacDonald et al.

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