N,N'-bridged-bis[2-alkyl-2-hydroxyethylamines]

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260472, 26050117, 2605012, 2605676P, 2605705P, 260584R, 260584A, 424316, 424325, 424330, C07C 9114, A61K 3113

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040228339

ABSTRACT:
N,N'-Bridged-bis[(O and/or N-substituted)-2-alkyl-2-hydroxyethylamines] of the formula ##STR1## are prepared by condensing an epoxide of the formula ##STR2## and a diamine of the formula R'NH-X-NHR'. The products and dicarbanilates, acid-addition salts, N,N'-dioxides and N,N'-diammonium quaternary salts derived therefrom have antibacterial activity in vitro and are useful as antibacterial agents.

REFERENCES:
patent: 2271378 (1942-01-01), Searle
patent: 2901461 (1959-08-01), Auerbach et al.
patent: 3131220 (1964-04-01), Zirkle
patent: 3317469 (1967-05-01), Feichtinger et al.
patent: 3524883 (1970-08-01), Kersner et al.
Diana et al., CA 82:170033y (1975).

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