N,N'-Bridged-bis(2-alkyl-2-hydroxyethylamine) dioxides

Details N,N'-Bridged-bis(2-alkyl-2-hydroxyethylamine) dioxides N,N'-Bridged-bis(2-alkyl-2-hydroxyethylamine) dioxides

1976-11-08

1978-04-18

Wyman, Daniel E.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

26050117, 2605012, 260563R, 2605676P, 2605705P, 424316, 424325, 424330, 560 24, C07C 9112, C07C 9114, A61K 3113

Patent

active

040851443

ABSTRACT:
N,N'-Bridged-bis[(O and/or N-substituted)-2-alkyl-2-hydroxyethylamines] of the formula ##STR1## are prepared by condensing an epoxide of the formula ##STR2## and a diamine of the formula R'NH--X--NHR'. The products and dicarbanilates, acid-addition salts, N,N'-dioxides and N,N'-diammonium quaternary salts derived therefrom have antibacterial activity in vitro and are useful as antibacterial agents.

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patent: 3131220 (1964-04-01), Zirkle
patent: 3197509 (1965-07-01), Drew et al.
patent: 3317469 (1967-05-01), Feichtinger et al.
patent: 3328467 (1967-06-01), Hamilton
patent: 3524883 (1970-08-01), Kersnar et al.
patent: 3555095 (1971-01-01), Slagel

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