N,N'-Bis[substituted-1,2,3,4-tetrahydroisoquinolinolyl]disulfony

Details N,N'-Bis[substituted-1,2,3,4-tetrahydroisoquinolinolyl]disulfony N,N'-Bis[substituted-1,2,3,4-tetrahydroisoquinolinolyl]disulfony

1980-06-13

1982-02-16

Daus, Donald G.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

546139, 546140, 546146, A61K 3147, C07D21716

Patent

active

043159354

ABSTRACT:
Imidodisulfamide derivatives useful in the treatment of allergic conditions are prepared by reaction of an appropriately substituted tetrahydroisoquinoline and bis(chlorosulfonyl)imide in the presence of a tertiary amine.

REFERENCES:
patent: 3882148 (1975-05-01), Augstein et al.
patent: 4179507 (1979-12-01), Stenlake et al.
patent: 4192877 (1980-03-01), Savarese et al.
patent: 4252818 (1981-02-01), Rokach et al.
"Chem. Eng. News", May 11, 1970, pp. 103-104.
Appleton et al., "J. Med. Chem.", vol. 20, 1970, pp. 371-379.
Chand, "Agents and Action", vol. 912, 1979, pp. 133-140.

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